The U.S. Centers for Disease Control and Prevention (CDC) is recommending moderately to severely immunocompromised people receive an additional dose of mRNA COVID-19 vaccine (Pfizer or Moderna).
People who are moderately to severely immunocompromised are especially vulnerable to COVID-19 because they are more at risk of serious, prolonged illness. Studies indicate some immunocompromised people don’t always build the same level of immunity after vaccination the way non-immunocompromised people do, and may benefit from an additional dose to ensure adequate protection against COVID-19. Emerging data suggests that immunocompromised people who have low or no protection after two doses of mRNA vaccines may have an improved response after an additional dose of the same vaccine.
The updated CDC recommendation includes people who have:
CDC recommends people talk to their healthcare provider about their medical condition, and whether getting an additional dose is appropriate for them.
This project was funded in part by a cooperative agreement with the Centers for Disease Control and Prevention (grant number NU50CK000580). The Centers for Disease Control and Prevention is an agency within the Department of Health and Human Services (HHS). The contents of this resource center do not necessarily represent the policy of CDC or HHS and should not be considered an endorsement by the Federal Government.